• Alternative Names :
• Mitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2), TIMM8B, DDP2 DDPL TIM8B

• Antigen :
• TIMM8B

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• HRP

• Description :
• Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Mitochondrial import inner membrane translocase subunit Tim8 B protein (33-83AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side

• Uniprot :
• Q9Y5J9

• Database Links :
• 
  

  HGNC:11818

  OMIM:606659

  KEGG:hsa:26521

  STRING:9606.ENSP00000438455

  UniGene:Hs.279915

• Function :
• Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).

• Protein Families :
• Small Tim family

• Research Area :
• Others

• Tissue Specificity :
• Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :