• Alternative Names :
• Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2), NR2C1, TR2

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

• Host :
• Rabbit, Rabbit

• Immunogen :
• Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA), Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus, Nucleus, PML body, Nucleus, Nucleus, PML body

• Uniprot :
• P13056

• Database Links :
• 
  

  HGNC:7971

  OMIM:601529

  KEGG:hsa:7181

  STRING:9606.ENSP00000333275

  UniGene:Hs.108301

  ,
  

  HGNC:7971

  OMIM:601529

  KEGG:hsa:7181

  STRING:9606.ENSP00000333275

  UniGene:Hs.108301

• Function :
• Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

• Protein Families :
• Nuclear hormone receptor family, NR2 subfamily, Nuclear hormone receptor family, NR2 subfamily

• Research Area :
• Epigenetics and Nuclear Signaling, Epigenetics and Nuclear Signaling

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified, Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :
• 

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :