• Alternative Names :
• Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM), CAPN6, CALPM CANPX

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Calpain-6 protein (195-494AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, perinuclear region, Cytoplasm, cytoskeleton, spindle

• Uniprot :
• Q9Y6Q1

• Database Links :
• 
  

  HGNC:1483

  OMIM:300146

  KEGG:hsa:827

  STRING:9606.ENSP00000317214

  UniGene:Hs.496593

• Function :
• Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity).

• Protein Families :
• Peptidase C2 family

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Expressed only in placenta.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :