• Alternative Names :
• RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog), RGP1, KIAA0258

• Antigen :
• RGP1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• FITC

• Description :
• The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human RAB6A-GEF complex partner protein 2 protein (56-350AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, cytosol, Membrane

• Uniprot :
• Q92546

• Database Links :
• 
  

  HGNC:21965

  OMIM:615742

  KEGG:hsa:9827

  STRING:9606.ENSP00000367318

  UniGene:Hs.493804

• Function :
• The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.

• Protein Families :
• RGP1 family

• Research Area :
• Signal Transduction

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :