• Alternative Names :
• E3 ubiquitin-protein ligase RNF182 (EC 2.3.2.27) (RING finger protein 182) (RING-type E3 ubiquitin transferase RNF182), RNF182

• Antigen :
• RNF182

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• Biotin

• Description :
• E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human E3 ubiquitin-protein ligase RNF182 protein (1-160AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Membrane, Multi-pass membrane protein, Cytoplasm

• Uniprot :
• Q8N6D2

• Database Links :
• 
  

  HGNC:28522

  KEGG:hsa:221687

  STRING:9606.ENSP00000420465

  UniGene:Hs.111164

• Function :
• E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.

• Research Area :
• Cell Biology

• Tissue Specificity :
• Up-regulated in neuronal cells subjected to cell death-inducing injuries, such as oxygen and glucose deprivation (at protein level). Could be up-regulated in Alzheimer disease brains.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :