• Alternative Names :
• Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac), RAPGEF5, GFR KIAA0277 MRGEF

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Rap guanine nucleotide exchange factor 5 protein (201-444AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Uniprot :
• Q92565

• Database Links :
• 
  

  HGNC:16862

  OMIM:609527

  KEGG:hsa:9771

  STRING:9606.ENSP00000343656

  UniGene:Hs.174768

• Function :
• Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.

• Pathway :
• Ras signaling pathway Rap1 signaling pathway

• Research Area :
• Neuroscience

• Tissue Specificity :
• Widely expressed with highest levels in brain.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :