• Alternative Names :
• Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8), SENP8, DEN1 NEDP1 PRSC2

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Sentrin-specific protease 8 protein (1-212AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.

• Species :
• Homo Sapiens (Human)

• Uniprot :
• Q96LD8

• Database Links :
• 
  

  HGNC:22992

  OMIM:608659

  KEGG:hsa:123228

  STRING:9606.ENSP00000340505

  UniGene:Hs.513002

• Function :
• Protease that catalyzes two essential functions in the NEDD8 pathway

• Protein Families :
• Peptidase C48 family

• Research Area :
• Cell Biology

• Tissue Specificity :
• Broadly expressed, with highest levels in kidney and pancreas.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :