• Alternative Names :
• Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25), MED30, THRAP6 TRAP25

• Antigen :
• MED30

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• FITC

• Description :
• Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Mediator of RNA polymerase II transcription subunit 30 protein (67-165AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Uniprot :
• Q96HR3

• Database Links :
• 
  

  HGNC:23032

  OMIM:610237

  KEGG:hsa:90390

  STRING:9606.ENSP00000297347

  UniGene:Hs.492612

• Function :
• Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

• Protein Families :
• Mediator complex subunit 30 family

• Research Area :
• Epigenetics and Nuclear Signaling

• Tissue Specificity :
• Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :