• Alternative Names :
• DPH3 homolog (CSL-type zinc finger-containing protein 2) (DelGEF-interacting protein 1) (DelGIP1), DPH3, DESR1 ZCSL2

• Antigen :
• DPH3

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• HRP

• Description :
• Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

• Host :
• Rabbit

• Immunogen :
• Recombinant Human DPH3 homolog protein (1-82AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, Nucleus

• Uniprot :
• Q96FX2

• Database Links :
• 
  

  HGNC:27717

  OMIM:608959

  KEGG:hsa:285381

  STRING:9606.ENSP00000419599

  UniGene:Hs.388087

• Function :
• Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

• Protein Families :
• DPH3 family

• Research Area :
• Cell Biology

• Tissue Specificity :
• Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :