• Alternative Names :
• NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD), ND-75, ND75

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.

• Host :
• Rabbit

• Immunogen :
• Recombinant Drosophila melanogaster NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial protein (28-315AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Drosophila melanogaster

• Regulatory :
• RUO

• Relevance :
• Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.

• Species :
• Drosophila Melanogaster (Fruit Fly)

• Subcellular Location :
• Mitochondrion inner membrane

• Uniprot :
• Q94511

• Database Links :
• 
  

  KEGG:dme:Dmel_CG2286

  STRING:7227.FBpp0071128

  UniGene:Dm.6840

• Function :
• Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity).

• Protein Families :
• Complex I 75 kDa subunit family

• Research Area :
• Others

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :