• Alternative Names :
• Circadian clock protein PASD1 (Cancer/testis antigen 63) (CT63) (OX-TES-1) (PAS domain-containing protein 1), PASD1

• Antigen :
• PASD1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• FITC

• Description :
• Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body (PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components (PubMed:25936801). Inhibits circadian clock function in cancer cells, when overexpressed (PubMed:25936801).

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Circadian clock protein PASD1 protein (301-600AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body (PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components (PubMed:25936801). Inhibits circadian clock function in cancer cells, when overexpressed (PubMed:25936801).

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Isoform 1: Nucleus, Note=Associates preferentially at the periphery of the nucleus with heterochromatin (PubMed:25936801), SUBCELLULAR LOCATION: Isoform 2: Nucleus

• Uniprot :
• Q8IV76

• Database Links :
• 
  

  HGNC:20686

  OMIM:300993

  KEGG:hsa:139135

  STRING:9606.ENSP00000359382

  UniGene:Hs.160594

• Function :
• Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body

• Research Area :
• Epigenetics and Nuclear Signaling

• Tissue Specificity :
• Testis-specific (PubMed:25936801). Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific (PubMed:15162151). Found in histologically normal tissues from patients with uterus, lung

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :