• Alternative Names :
• Tubulin polyglutamylase TTLL6 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 6), TTLL6, TTL.6

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Tubulin polyglutamylase TTLL6 protein (121-310AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell projection, cilium, Cytoplasm, cytoskeleton, cilium basal body

• Uniprot :
• Q8N841

• Database Links :
• 
  

  HGNC:26664

  OMIM:610849

  KEGG:hsa:284076

  STRING:9606.ENSP00000377043

  UniGene:Hs.91930

• Function :
• Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS.

• Protein Families :
• Tubulin--tyrosine ligase family

• Research Area :
• Others

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :