• Alternative Names :
• Interactor of HORMAD1 protein 1 (Cancer/testis antigen 74) (CT74) (Coiled-coil domain-containing protein 36), CCDC36, IHO1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Interactor of HORMAD1 protein 1 protein (11-592AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Chromosome

• Uniprot :
• Q8IYA8

• Database Links :
• 
  

  HGNC:27945

  KEGG:hsa:339834

  STRING:9606.ENSP00000296449

  UniGene:Hs.631931

• Function :
• Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

• Research Area :
• Cell Biology

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :