Rat Dorsal Root Ganglion Neurons (rDRGN)

Product Description

A ganglion is a group of nerve cells forming a nerve center, especially one located outside the brain or spinal cord. Dorsal root ganglion is a group of sensory nerve cell bodies. They pass sensory information to neurons in the spinal cord so it can be analyzed by the brain. In anatomy and neurology, the dorsal root ganglion (or spinal ganglion) is a nodule on a dorsal root that contains cell bodies of neurons in afferent spinal nerves. Dorsal root ganglion cells are pseudounipolar cells. Pseudounipolar cells have 2 axons rather than an axon and dendrite. One axon extends centrally toward the spinal cord; the other axon extends toward the skin or muscle.. Cultured adult rat dorsal root ganglion (DRG) neurons can be used to study depolarization-induced Ca²⁺ mobilization and the effects of intracellular Ca²⁺ depletion on neurite outgrowth. DRGs are very useful in neurotoxicity assessment & other drug screening studies.

Rat Dorsal Root Ganglion Neurons (rDRGN) provided by iXCells Biotechnologies are derived from spinal cords of normal embryonic rat. >500,000 cells are cryopreserved upon isolation. Each lot was tested for proper morphology, Stain positive for beta III-Tubulin (TUJ1), Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

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