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Home / Primary Antibodies

ZO2 Antibody / TJP2 (RQ6401)

SKU : BHA17111036

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NSJ Bioreagents

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Mfr.No.	RQ6401
Clonality	Polyclonal
Description	TJP2 (Tight Junction Protein 2), also known as Zona Occludens 2 or ZO2 is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al.(1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. TJP2 lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction. Using in vitro assays and immunoprecipitation studies, Itoh et al.(1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50% of the level at birth(P0).
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids QEAQNARIEIAQKHPDIYAVPIK were used as the immunogen for the ZO2 antibody.
Isotype	IgG
Predicted Reactivity	Human, Monkey, Mouse, Rat
Reactivity	Human, Monkey, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic, nuclear, cell junctions

Uniprot	Q9UDY2

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Format	Purified
Purification	Antigen affinity purified
Storage	After reconstitution, the ZO2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, IF, FACS
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17111036	RQ6401	100 ug	$419		Add to Cart

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