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Home / Antibodies

ZO-2 Antibody (R31060)

SKU : BHA17104563

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Mfr.No.	R31060
Clonality	Polyclonal
Description	Tight Junction Protein 2, also known as Zona occludens 2 or ZO-2 is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins (TJPs), or zonulae occludentes, belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al.(1994) mapped the gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. It lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction. Using in vitro assays and immunoprecipitation studies, Itoh et al.(1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50% of the level at birth(P0).
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to human Zona occludens 2 (SEHSKRGYYGQSARYRDTEL) was used as the immunogen for this ZO-2 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q9UDY2

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the ZO-2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, IHC-F
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104563	R31060	100 ug	$419		Add to Cart

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