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Home / Antibodies

YWHAZ Antibody

SKU : BHA10558077

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA912524
Alternative Names	14-3-3 protein zeta/delta; 1433Z; 143Z; FAS; Factor activating exoenzyme S
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.Zupan L.A., J. Biol. Chem. 267:8707-8710(1992).Seluja G.A., Biochim. Biophys. Acta 1395:281-287(1998).Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human 14-3-3 ζ.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Zupan L.A., J. Biol. Chem. 267:8707-8710(1992). Seluja G.A., Biochim. Biophys. Acta 1395:281-287(1998). Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total 14-3-3 ζ protein.
Subcellular Location	Cytoplasm, Melanosome

Uniprot	P63104
Database Links	HGNC:12855 OMIM:601288 KEGG:hsa:7534 STRING:9606.ENSP00000309503 UniGene:Hs.492407
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Pathway	Hippo signaling pathway PI3K-Akt signaling pathway Cell cycle
Protein Families	14-3-3 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558077	CSB-PA912524	100ul	$297		Add to Cart

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