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Home / Antibodies

YWHAH Antibody

SKU : BHA10559376

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA213006
Alternative Names	14-3-3 protein eta; Protein AS1; YWHAH; YWHA1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.Swanson K.D., Biochim. Biophys. Acta 1216:145-148(1993).Ichimura-Ohshima Y., J. Neurosci. Res. 31:600-605(1992).Muratake T., Mol. Neurobiol. 11:223-230(1995).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human 14-3-3 η.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. Swanson K.D., Biochim. Biophys. Acta 1216:145-148(1993). Ichimura-Ohshima Y., J. Neurosci. Res. 31:600-605(1992). Muratake T., Mol. Neurobiol. 11:223-230(1995).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total 14-3-3 η protein.

Uniprot	Q04917
Database Links	HGNC:12853 OMIM:113508 KEGG:hsa:7533 STRING:9606.ENSP00000248975 UniGene:Hs.226755
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Pathway	Hippo signaling pathway PI3K-Akt signaling pathway Cell cycle
Protein Families	14-3-3 family
Tissue Specificity	Expressed mainly in the brain and present in other tissues albeit at lower levels.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559376	CSB-PA213006	100ul	$297		Add to Cart

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