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Home / Antibodies

YWHAE Antibody

SKU : BHA10558075

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA205505
Alternative Names	14-3-3E; 143E; KCIP-1; Mitochondrial import stimulation factor L subunit; Protein kinase C inhibitor protein-1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.Conklin D.S., Proc. Natl. Acad. Sci. U.S.A. 92:7892-7896(1995).Jin D.-Y., Nature 382:308-308(1996).Chong S.S., ome Res. 6:735-741(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human 14-3-3 ε.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Conklin D.S., Proc. Natl. Acad. Sci. U.S.A. 92:7892-7896(1995). Jin D.-Y., Nature 382:308-308(1996). Chong S.S., ome Res. 6:735-741(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total 14-3-3 ε protein.
Subcellular Location	Nucleus, Cytoplasm, Melanosome

Uniprot	P62258
Database Links	HGNC:12851 OMIM:605066 KEGG:hsa:7531 STRING:9606.ENSP00000264335 UniGene:Hs.513851
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm
Pathway	Hippo signaling pathway PI3K-Akt signaling pathway Cell cycle Neurotrophin signaling pathway
Protein Families	14-3-3 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558075	CSB-PA205505	100ul	$297		Add to Cart

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