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Home / Primary Antibodies

YEATS4 Antibody

SKU : BHA10557786

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA105916
Alternative Names	YEATS domain-containing protein 4; Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.Fischer U., Hum. Mol. Genet. 6:1817-1822(1997).Harborth J., J. Biol. Chem. 275:31979-31985(2000).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GAS41.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Fischer U., Hum. Mol. Genet. 6:1817-1822(1997). Harborth J., J. Biol. Chem. 275:31979-31985(2000). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GAS41 protein.
Subcellular Location	Nucleus

Uniprot	O95619
Database Links	HGNC:24859 OMIM:602116 KEGG:hsa:8089 STRING:9606.ENSP00000247843 UniGene:Hs.4029
Function	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Tissue Specificity	Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557786	CSB-PA105916	100ul	$297		Add to Cart

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