Loss of heterozygosity 11 chromosomal region 2 gene A protein; Breast cancer suppressor candidate 1; BCSC-1; LOH11CR2A; BCSC1
Categories
Primary Antibodies
Clonality
polyclonal
Description
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.Martin E.S., Proc. Natl. Acad. Sci. U.S.A. 100:11517-11522(2003).The MGC Project Team, Genome Res. 14:2121-2127(2004).Monaco C., Genomics 46:217-222(1997).
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human LHR2A.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Martin E.S., Proc. Natl. Acad. Sci. U.S.A. 100:11517-11522(2003). The MGC Project Team, Genome Res. 14:2121-2127(2004). Monaco C., Genomics 46:217-222(1997).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LHR2A protein.
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Tissue Specificity
Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.