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Home / Primary Antibodies

von Willebrand Factor Antibody / vWF (V2299SAF)

SKU : BHA17123653

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NSJ Bioreagents

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Mfr.No.	V2299SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	von Willebrand Factor (vWF) is a glycoprotein produced by bone marrow cells and endothelial cells lining the inside surface of blood vessels. Its primary function is platelet adhesion, binding to Factor VIII, collagen and platelets, to coagulate blood at the site of wounding. The enzyme VWFCP, or vWF-cleaving protease, facilitates clotting by cutting the protein into subunits, increasing its binding capacity.Deficiency or dysfunction of the protein increases the tendency of wounds to bleed, or to bleed more. Over 300 gene mutations have been identified and classified into three types. Type 1 von Willebrand Factor disease is characterized by reduced amounts in the bloodstream, Type 2 by reduced binding ability and Type 3 by a nonfunctional protein.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human protein fragment was used as the immunogen for this von Willebrand Factor antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Variations in protocols, secondaries and substrates may require the von Willebrand Factor antibody to be titered for optimal performance.1. FFPE staining requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.

Format	Purified
Purity	Protein G purified von Willebrand Factor antibody
Storage	Store the von Willebrand Factor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123653	V2299SAF-100UG	100 ug	$499		Add to Cart

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