Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.Daniela Bellomo, Circ. Res., Feb 2000; 86: 29. Maen Abdelrahim, Cancer Res., Apr 2007; 67: 3286 - 3294. Arne W. Mould, Circ. Res., Sep 2005; 97: e60 - e70. Jean Christophe Gollmer, Neuro-oncol, Apr 2000; 2: 80 - 86.
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human VEGFB.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Daniela Bellomo, Circ. Res., Feb 2000; 86: 29. Maen Abdelrahim, Cancer Res., Apr 2007; 67: 3286 - 3294. Arne W. Mould, Circ. Res., Sep 2005; 97: e60 - e70. Jean Christophe Gollmer, Neuro-oncol, Apr 2000; 2: 80 - 86.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total VEGFB protein.
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.