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Home / Primary Antibodies

VEGF Receptor 2 Antibody / VEGFR2 / KDR (V8272SAF)

SKU : BHA17127361

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NSJ Bioreagents

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Mfr.No.	V8272SAF-100UG
Clonality	Monoclonal (rat origin)
Description	This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rat
Immunogen Region	Recombinant full-length Mouse VEGFR2 protein was used as the immunogen for this VEGFR2 antibody.
Isotype	Rat IgG1, kappa
Species Reactivity	Mouse
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P35918

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the VEGFR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Neutralizing, Blocking, Inhibition, WB
Description	Western blot (Non-reducing): 2-5ug/ml,Blocks binding of VEGF to VEGF-R2,Inhibits VEGF-induced signalingformat),Blocks tumor growth in mice

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/vegfr2-antibody-dc101-v8272" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127361	V8272SAF-100UG	100 ug	$499		Add to Cart

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