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Home / Antibodies

VASH1 Antibody

SKU : BHA10558900

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA149592
Alternative Names	Vasohibin-1; VASH1; KIAA1036; VASH;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.Kikuno R., DNA Res. 6:197-205(1999).Bechtel S., BMC Genomics 8:399-399(2007).Heilig R., Nature 421:601-607(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human VASH1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. Kikuno R., DNA Res. 6:197-205(1999). Bechtel S., BMC Genomics 8:399-399(2007). Heilig R., Nature 421:601-607(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total VASH1 protein.
Subcellular Location	Secreted

Uniprot	Q7L8A9
Database Links	HGNC:19964 OMIM:609011 KEGG:hsa:22846 STRING:9606.ENSP00000167106 UniGene:Hs.525479
Function	Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.
Protein Families	Vasohibin family
Tissue Specificity	Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of atherosclerotic lesions.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558900	CSB-PA149592	100ul	$297		Add to Cart

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