Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension(EH).
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
polyclonal
Description
Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension (EH).
Host
Rabbit
Immunogen
guanylate cyclase activator 2B(uroguanylin)
Isotype
IgG
Molecular Weight
12 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
secreted
Synonyms
GCAP II, GCAP II Uroguanylin, Guanylate cyclase activator 2B, GUCA2B, UGN
Antigen
Uroguanylin
Uniprot
Q16661
Gene Id
2981
Research Area
Signal Transduction
Weight
12kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)