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Home / Primary Antibodies

UNG Antibody

SKU : BHA10557804

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA077550
Alternative Names	DGU; EC 3.2.2.-; UDG; UNG15; uracil-DNA glycosylase
Categories	Primary Antibodies
Clonality	polyclonal
Description	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. HAMAP-Rule MF_03166Olsen L.C., EMBO J. 8:3121-3125(1989).Haug T., FEBS Lett. 353:180-184(1994).Nilsen H., Nucleic Acids Res. 25:750-755(1997).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human UNG.
Involvement In Disease	Immunodeficiency with hyper-IgM 5 (HIGM5)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. HAMAP-Rule MF_03166 Olsen L.C., EMBO J. 8:3121-3125(1989). Haug T., FEBS Lett. 353:180-184(1994). Nilsen H., Nucleic Acids Res. 25:750-755(1997).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total UNG protein.
Subcellular Location	Isoform 1: Mitochondrion, SUBCELLULAR LOCATION: Isoform 2: Nucleus

Uniprot	P13051
Database Links	HGNC:12572 OMIM:191525 KEGG:hsa:7374 STRING:9606.ENSP00000242576 UniGene:Hs.191334
Function	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Pathway	DNA repair pathway
Protein Families	Uracil-DNA glycosylase (UDG) superfamily, UNG family
Tissue Specificity	Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557804	CSB-PA077550	100ul	$297		Add to Cart

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