Tubulin-specific chaperone A, also called Tubulin-folding cofactor A (CFA), is a protein that in humans is encoded by the TBCA gene. The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alteatively spliced transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Immunogen Region
Recombinant human protein (amino acids M1-A108) was used as the immunogen for the TBCA antibody.
Isotype
Rabbit IgG
Reactivity
Human
Recombinant
No
Uniprot
O75347
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the TBCA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.