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Home / Primary Antibodies

TRP1 / Tyrosinase-Related Protein-1 Antibody (V2917SAF)

SKU : BHA17124506

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NSJ Bioreagents

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Mfr.No.	V2917SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human, Mouse
Note	Optimal dilution of the TRP1 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	P17643

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124506	V2917SAF-100UG	100 ug	$499		Add to Cart

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