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Home / Primary Antibodies

TrkC Antibody (R31098)

SKU : BHA17104591

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NSJ Bioreagents

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Mfr.No.	R31098
Clonality	Polyclonal
Description	NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al.(1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain; in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al.(2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3. Signaling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. The protein is a heavily glycosylated molecule with 13 potential N-linked glycosylation sites within the extracellular domain.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the N-terminus of human TrkC (QLWQEQGEAKLNSQN) was used as the immunogen for this TrkC antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	Q16288

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the TrkC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104591	R31098	100 ug	$419		Add to Cart

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