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Home / Primary Antibodies

TRIP4 Antibody

SKU : BHA10557933

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA278043
Alternative Names	Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TRIP-4; TRIP4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function By similarity.Kim H.J., Mol. Cell. Biol. 19:6323-6332(1999).Lee J.W., Mol. Endocrinol. 9:243-254(1995).Jung D.-J., Mol. Cell. Biol. 22:5203-5211(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TRIP4.
Involvement In Disease	Spinal muscular atrophy with congenital bone fractures 1 (SMABF1); Muscular dystrophy, congenital, Davignon-Chauveau type (MDCDC)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function By similarity. Kim H.J., Mol. Cell. Biol. 19:6323-6332(1999). Lee J.W., Mol. Endocrinol. 9:243-254(1995). Jung D.-J., Mol. Cell. Biol. 22:5203-5211(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TRIP4 protein.
Subcellular Location	Nucleus, Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Uniprot	Q15650
Gene Id	9325
Database Links	HGNC:12310 OMIM:604501 KEGG:hsa:9325 STRING:9606.ENSP00000261884 UniGene:Hs.500340
Function	Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation
Weight	66,146 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557933	CSB-PA278043	100ul	$297		Add to Cart

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