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Home / Antibodies

Trem1 Antibody (R30663)

SKU : BHA17104266

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NSJ Bioreagents

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Mfr.No.	R30663
Clonality	Polyclonal
Description	Triggering receptor expressed on myeloid cells-1, is encoded by TREM1 gene. Expression is seen is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide(LPS), gram-negative bacteria, and fungi. Cross-linking of TREM1 on neutrophils induces interleukin-8(IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1(MCP1, or SCYA2) and tumor necrosis factor(TNF); MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Engagement also induces upregulation of adhesion molecules(e.g., ITGB1) and costimulatory molecules(e.g., CD40). TREM1 is associated with DAP12(TYROBP), a molecule frequently associated with activating receptors.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 74-90 (FTRPSEVHMGKFTLKHD-mouse) were used as the immunogen for this Trem1 antibody.
Isotype	IgG
Predicted Reactivity	Mouse, Rat
Reactivity	Mouse, Rat
Recombinant	No

Uniprot	Q9JKE2

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Trem1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104266	R30663	100 ug	$419		Add to Cart

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