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Home / Antibodies

TOP1MT Antibody / Topoisomerase I mitochondrial (V7684SAF)

SKU : BHA17126875

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NSJ Bioreagents

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Mfr.No.	V7684SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human protein was used as the immunogen for the TOP1MT antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	Q969P6

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the TOP1MT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/top1mt-antibody-top1mt-568-v7684" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126875	V7684SAF-100UG	100 ug	$499		Add to Cart

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