Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore By similarity.Goping I.S., FEBS Lett. 373:45-50(1995).Seki N., FEBS Lett. 375:307-310(1995).Hernandez J.M., Gene 239:283-291(1999)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human TOMM20.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore By similarity.
Goping I.S., FEBS Lett. 373:45-50(1995). Seki N., FEBS Lett. 375:307-310(1995). Hernandez J.M., Gene 239:283-291(1999)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total TOMM20 protein.
Subcellular Location
Mitochondrion outer membrane, Single-pass membrane protein
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).
Protein Families
Tom20 family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.