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Home / Antibodies

TOLLIP Antibody

SKU : BHA10558907

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA571897
Alternative Names	adapter protein; FLJ33531; IL-1RAcPIP; TOLIP; toll interacting protein
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.Burns K., Nat. Cell Biol. 2:346-351(2000).Wiemann S., Genome Res. 11:422-435(2001).Zhang G., J. Biol. Chem. 277:7059-7065(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human TOLLIP.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Burns K., Nat. Cell Biol. 2:346-351(2000). Wiemann S., Genome Res. 11:422-435(2001). Zhang G., J. Biol. Chem. 277:7059-7065(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TOLLIPprotein.
Subcellular Location	Cytoplasm

Uniprot	Q9H0E2
Database Links	HGNC:16476 OMIM:606277 KEGG:hsa:54472 STRING:9606.ENSP00000314733 UniGene:Hs.368527
Function	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity
Pathway	Toll-like receptor signaling pathway
Protein Families	Tollip family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558907	CSB-PA571897	100ul	$297		Add to Cart

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