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Home / Primary Antibodies

TNFSF15 Antibody / VEGI / TL1A (V3636SAF)

SKU : BHA17125368

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NSJ Bioreagents

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Mfr.No.	V3636SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A/TNFSF15/VEGI has been reported as a marker of poor prognosis in breast cancer.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	A full length human recombinant protein was used as the immunogen for this recombinant TNFSF15 antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Titration of the recombinant TNFSF15 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	O95150

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant TNFSF15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125368	V3636SAF-100UG	100 ug	$499		Add to Cart

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