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Home / Antibodies

TNFRSF10D Antibody

SKU : BHA10558893

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA031451
Alternative Names	Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to it cannot but according to it can induce the NF-kappa-B pathway.Marsters S.A., Curr. Biol. 7:1003-1006(1997).Degli-Esposti M.A., Immunity 7:813-820(1997).Pan G., FEBS Lett. 424:41-45(1998).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TNFRSF10D.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to it cannot but according to it can induce the NF-kappa-B pathway. Marsters S.A., Curr. Biol. 7:1003-1006(1997). Degli-Esposti M.A., Immunity 7:813-820(1997). Pan G., FEBS Lett. 424:41-45(1998).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TNFRSF10D protein.
Subcellular Location	Membrane, Single-pass type I membrane protein

Uniprot	Q9UBN6
Database Links	HGNC:11907 OMIM:603614 KEGG:hsa:8793 STRING:9606.ENSP00000310263 UniGene:Hs.213467
Function	Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed
Pathway	Apoptosis Necroptosis Natural killer cell mediated cytotoxicity
Tissue Specificity	Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558893	CSB-PA031451	100ul	$297		Add to Cart

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