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Home / Primary Antibodies

TMPRSS3 Antibody

SKU : BHA10559310

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA000297
Alternative Names	Transmembrane protease; serine 3; EC 3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival By similarity. Activates ENaC (in vitro).Underwood L.J., Biochim. Biophys. Acta 1502:337-350(2000).Scott H.S., Nat. Genet. 27:59-63(2001).Clark H.F., Genome Res. 13:2265-2270(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human TMPRSS3.
Involvement In Disease	Deafness, autosomal recessive, 8 (DFNB8)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival By similarity. Activates ENaC (in vitro). Underwood L.J., Biochim. Biophys. Acta 1502:337-350(2000). Scott H.S., Nat. Genet. 27:59-63(2001). Clark H.F., Genome Res. 13:2265-2270(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TMPRSS3 protein.
Subcellular Location	Endoplasmic reticulum membrane, Single-pass type II membrane protein

Uniprot	P57727
Database Links	HGNC:11877 OMIM:601072 KEGG:hsa:64699 STRING:9606.ENSP00000291532 UniGene:Hs.208600
Function	Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
Protein Families	Peptidase S1 family
Tissue Specificity	Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559310	CSB-PA000297	100ul	$297		Add to Cart

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