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Home / Antibodies

TMEM30B Antibody

SKU : BHA10558098

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA194152
Alternative Names	Cell cycle control protein 50B; Transmembrane protein 30B; TMEM30B; CDC50B; CC50B
Categories	Primary Antibodies
Clonality	polyclonal
Description	Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate Probable. Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.The MGC Project Team, Genome Res. 14:2121-2127(2004).Katoh Y., Oncol. Rep. 12:939-943(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TMEM30B.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate Probable. Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. The MGC Project Team, Genome Res. 14:2121-2127(2004). Katoh Y., Oncol. Rep. 12:939-943(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TMEM30B protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	Q3MIR4
Database Links	HGNC:27254 OMIM:611029 KEGG:hsa:161291 STRING:9606.ENSP00000347930 UniGene:Hs.146180
Function	Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
Protein Families	CDC50/LEM3 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558098	CSB-PA194152	100ul	$297		Add to Cart

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