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Home / Primary Antibodies

TLR4 Antibody (V2897SAF)

SKU : BHA17124482

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NSJ Bioreagents

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Mfr.No.	V2897SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular pattes that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different pattes of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant human protein was used as the immunogen for the TLR4 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human
Note	Optimal dilution of the TLR4 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

Uniprot	O00206

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the TLR4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Functional studies
Description	Functional studies (order BSA/sodium azide-free format)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124482	V2897SAF-100UG	100 ug	$499		Add to Cart

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