Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 262-290 from the human protein was used as the immunogen for this TLE4 antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the TLE4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
Q04727
Format
Ascites
Purity
Ascites
Storage
Aliquot the TLE4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.