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Home / Primary Antibodies

TLE2 Antibody

SKU : BHA10557901

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA206010
Alternative Names	Transducin-like enhancer protein 2; ESG2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity.Stifani S., Nat. Genet. 2:119-127(1992).Grimwood J., Nature 428:529-535(2004).Grbavec D., Eur. J. Biochem. 258:339-349(1998).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human TLE2.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity. Stifani S., Nat. Genet. 2:119-127(1992). Grimwood J., Nature 428:529-535(2004). Grbavec D., Eur. J. Biochem. 258:339-349(1998).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TLE2 protein.
Subcellular Location	Nucleus

Uniprot	Q04725
Database Links	HGNC:11838 OMIM:601041 KEGG:hsa:7089 STRING:9606.ENSP00000262953 UniGene:Hs.332173
Function	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Protein Families	WD repeat Groucho/TLE family
Tissue Specificity	In all tissues examined, mostly in heart, brain, and muscle.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557901	CSB-PA206010	100ul	$297		Add to Cart

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