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Home / Antibodies

TIMP2 Antibody

SKU : BHA10559776

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA699608
Alternative Names	tissue inhibitor of metalloproteinase 2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.Dominique Trudel, AACR Meeting Abstracts, Mar 2004; 2004: 264. O. Alcazar, Invest. Ophthalmol. Vis. Sci., May 2007; 48: 5057. Isabelle Kazes, Blood, Nov 2000; 96: 3064 - 3069. Georgina S. Butler, J. Biol. Chem., Jan 1998; 273: 871.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human TIMP2.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. Dominique Trudel, AACR Meeting Abstracts, Mar 2004; 2004: 264. O. Alcazar, Invest. Ophthalmol. Vis. Sci., May 2007; 48: 5057. Isabelle Kazes, Blood, Nov 2000; 96: 3064 - 3069. Georgina S. Butler, J. Biol. Chem., Jan 1998; 273: 871.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TIMP2 protein.
Subcellular Location	Secreted

Uniprot	P16035
Database Links	HGNC:11821 OMIM:188825 KEGG:hsa:7077 STRING:9606.ENSP00000262768 UniGene:Hs.633514
Function	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Protein Families	Protease inhibitor I35 (TIMP) family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559776	CSB-PA699608	100ul	$297		Add to Cart

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