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Home / Antibodies

TIMP1 Antibody (V3596SAF)

SKU : BHA17125295

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NSJ Bioreagents

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Mfr.No.	V3596SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	TIMP1 is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 plays a crucial role in extracellular matrix (ECM) composition, wound healing, and pregnancy.The dysregulated activity of TIMP1 has been implicated in cancer. In pregnancy, TIMP1 plays a regulatory role in the process of implantation, particularly the cytotrophoblast invasion of the uterine endometrium. Additionally, it plays a role in regulating the transcriptional profile of fetal and placental tissues associated with the early stages of pregnancy. Studies attribute this role to a mechanism involving the chromatin structure at the TIMP1 promoter region, implicating new pharmaceutical possibilities for the therapeutic regulation of TIMP1. Accordingly, TIMP1 can be manipulated in vitro using techniques, like the TIMP1 knock-out. (Wiki)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	Recombinant human protein was used as the immunogen for this recombinant TIMP1 antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Optimal dilution of the recombinant TIMP1 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	P01033

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant TIMP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA: 2-4ug/ml (order BSA/azide-free format)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125295	V3596SAF-100UG	100 ug	$499		Add to Cart

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