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Home / Primary Antibodies

Thymidylate Synthase Antibody (F54315)

SKU : BHA17102788

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NSJ Bioreagents

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Mfr.No.	F54315, F54315-0.08ML, F54315-0.4ML
Antigen	Thymidylate Synthase
Clonality	Polyclonal
Description	Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 265-294 from the human protein was used as the immunogen for the Thymidylate Synthase Antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic, nuclear

Uniprot	P04818

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the Thymidylate Synthase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P, IF, FACS
Dilution	Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Immunofluorescence: 1:25,Flow cytometry: 1:25 (1x10e6 cells)

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102788-1	F54315-0.08ML	0.08ml	$165		Add to Cart
BHA17102788-2	F54315-0.4ML	0.4ml	$370		Add to Cart

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