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Home / Primary Antibodies / Polyclonal Antibodies

THRB Antibody - SPC-1314

BHA11917838
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+1 866.986.9598
Email
[email protected]
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Swissprot P10828
Accession Number NP_000452.2
Gene Id 7068
Target THRB
Research Area Cell Signaling, Growth Factors, Epigenetics and Nuclear Signaling, Neuroscience
Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Dilutions WB (1:1000), IHC (1:100), ELISA (1:5000); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Scientific Background There are three forms of the thyroid hormone receptor designated alpha-1, beta-1 and beta-2 that are able to bind thyroid hormone. There are two TR-alpha receptor splice variants encoded by the THRA gene and two TR-beta isoform splice variants encoded by the THRB gene. Thyroid hormone receptor beta-1 operates as a hormone-dependent transcriptional regulator that binds DNA sequences and is activated by 3,5,3'-l-triiodothyronine (T3). Thyroid hormone receptor beta-1 is important in vertebrate development, specifically in developing limbs and face. 9-cis-retinoic acid receptor (RXR) and retinoic acid receptor (RAR) receptor families are often associated with thyroid hormone receptor beta-1 and form homodimers and heterodimers.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~42kDa, endogenous levels of total Thyroid Hormone Receptor beta protein.
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications ELISA, IHC, WB
Description WB ; IHC ; ELISA
Dilution WB (1:1000), IHC (1:100), ELISA (1:5000); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Flamant F et al. (2006) Pharmacol Rev 58 (4): 705–11.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11917838-1 SPC-1314D Unconjugated 100 ul $286
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BHA11917838-2 SPC-1314D-A390 ATTO 390 100 ul $340
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BHA11917838-3 SPC-1314D-A488 ATTO 488 100 ul $339
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BHA11917838-4 SPC-1314D-A594 ATTO 594 100 ul $339
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BHA11917838-5 SPC-1314D-BI Biotin 100 ul $334
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BHA11917838-6 SPC-1314D-FITC FITC 100 ul $330
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