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Home / Primary Antibodies

TGFB1/2/3 Antibody / TGF Beta 1/2/3 (V2889SAF)

SKU : BHA17124471

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NSJ Bioreagents

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Mfr.No.	V2889SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This mAb recognizes TGF beta 1, 2 and 3. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80% identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFb's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Bovine TGF-beta2 protein was used as the immunogen for the TGF-beta antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the TGF-beta antibody should be determined by the researcher.

Uniprot	P01137, P10600, P61812

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the TGF-beta antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Cytokine neutralization, Functional assay, WB, ELISA, IF
Description	Cytokine neutralization (order BSA/sodium azide-free format),Functional assay (order BSA/sodium azide-free format),ELISA: 0.1-0.4ug/ml (detect); 2-8ug/ml (capture),Immunofluorescence: 8-25ug/ml,Weste blot: 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124471	V2889SAF-100UG	100 ug	$499		Add to Cart

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