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Home / Antibodies

TFAP2C Antibody

SKU : BHA10557987

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA036945
Alternative Names	AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.Williamson J.A., Genomics 35:262-264(1996).McPherson L.A., Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997).Deloukas P., Nature 414:865-871(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human AP2C.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Williamson J.A., Genomics 35:262-264(1996). McPherson L.A., Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997). Deloukas P., Nature 414:865-871(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total AP2C protein.
Subcellular Location	Nucleus

Uniprot	Q92754
Gene Id	7022
Database Links	HGNC:11744 OMIM:601602 KEGG:hsa:7022 STRING:9606.ENSP00000201031 UniGene:Hs.473152
Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Protein Families	AP-2 family
Weight	31,010 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557987	CSB-PA036945	100ul	$297		Add to Cart

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