The microtubule-associated proteins (MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein Tau appears to be enriched in axons. Tau is composed of 352 to 441 amino acids and migrate at 45-65KD. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. Tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of Alzheimers brain.
Formulation
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Host
Mouse
Immunogen Region
Bovine microtubule-associated proteins were used as the immunogen for this Tau antibody.
Isotype
IgG1
Predicted Reactivity
Human, bovine
Reactivity
bovine, Human
Recombinant
No
Gene Id
4137
Clone No
TAU-2
Format
Ascites
Purification
Unpurified ascites
Storage
After reconstitution, the Tau antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.