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Home / Antibodies

TAL1 (Ab-122) Antibody

SKU : BHA10557705

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA276394
Alternative Names	T-cell acute lymphocytic leukemia protein 1; SCL; TCL5;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation By similarity.Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).Gregory S.G., Nature 441:315-321(2006).Chen Q., J. Exp. Med. 172:1403-1408(1990)
Host	Rabbit, Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human TAL-1 around the phosphorylation site of serine 122 (Q-L-S(p)-P-P)., Synthesized non-phosphopeptide derived from Human TAL-1 around the phosphorylation site of serine 122 (Q-L-S(p)-P-P).
Involvement In Disease	A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.
Raised In	Rabbit
Reactivity	Human, Human, Mouse
Regulatory	RUO
Relevance	Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation By similarity. Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990). Gregory S.G., Nature 441:315-321(2006). Chen Q., J. Exp. Med. 172:1403-1408(1990)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TAL-1 protein.
Subcellular Location	Nucleus

Uniprot	P17542
Database Links	HGNC:11556 OMIM:187040 KEGG:hsa:6886 STRING:9606.ENSP00000294339 UniGene:Hs.705618
Function	Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).
Tissue Specificity	Leukemic stem cell.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze., Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557705	CSB-PA276394	100ul	$297		Add to Cart

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